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Thus, this study aimed to determine the effect of 10-week L-carnitine supplement (1.5 g/day) on frailty status and its biomarkers and also physical function, cognition, and nutritional status among prefrail older adults in Klang Valley, Malaysia

doi: 10.3389/fphar.2020.589114 Received 30 July 2020 Accepted 07 December 2020 Published 12 February 2021 Volume 11 - 2020 Edited by Paul Roos Ernsberger, Case Western Reserve University, United States Reviewed by Qinghe Meng, Upstate Medical University, United States Xandra Pereiro, University of the Basque Country, Spain Updates Copyright 2021 Zhou, Ma, Lin, Hao, Yu, Li, Xu and Kuang

It increases VEGF receptor activity to promote new blood vessel formation, enhances collagen synthesis and organization, activates the ERK1/2 signaling pathway for cell proliferation and migration, and modulates inflammatory responses to optimize healing conditions